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Date : 2006-03-24
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Cell Injury Cell Death and Adaptations ~ 4 CHAPTER 1 Cell Injury Cell Death and Adaptations myofilaments per cell which achieves improved performance and thus a balance between the demand and the cell’s functional capacity There may also be a switch of contractile proteins from adult to fetal or neonatal forms For example during muscle hypertrophy the αmyosin
Cell injury Clinical Gate ~ Cell injury may be reversible sublethal or irreversible lethal Reversible injury may require cellular adaptation but the cell survives Irreversible injury leads to death of the cell When cell death occurs in the living body the term necrosis is used At the cellular level there are many processes that can lead to necrosis
Cell damage Wikipedia ~ Causes Physical agents such as heat or radiation can damage a cell by literally cooking or coagulating their contents Impaired nutrient supply such as lack of oxygen or glucose or impaired production of adenosine triphosphate ATP may deprive the cell of essential materials needed to survive
Cell Injury Cell Death and Aging Pathology A Modern ~ cell injury and cell death an introduction An interest in the effects of disease and trauma is nothing new People have been pathologists observing the effects of disease since the dawn of recorded history likely before
Cell Injury Adaptation and Death MIT OpenCourseWare ~ Cell response to injury is not an allornothing phenomenon The stronger and the longer the stimulus the larger the damage Response to a given stimulus depends on the type status and genetic makeup of the injured cell Contrast ischemia in skeletal muscle tolerates 2 hours versus cardiac muscle tolerate 20
Robbins Chapter 1 Cell Injury Death ~ Reversible cell injury cell swelling detachment of ribosomes from granular and dissociation of polysomes into monosomes Fatty change encountered in cells invloved in fat metabolism hepatocyte myocardium Histologically characterized by pallor hydropic change vacuolar degeneration
Cellular Injury Necrosis Apoptosis ~ Cell injury results when cells are stressed and can no longer adapt Injury may progress through a reversible stage
cell injury Human pathology ~ cell injury Cell injury results when cells are stressed so severely that they are no longer able to adapt or when cells are exposed to inherently damaging agents Injury may progress through a reversible stage and culminate in cellular death
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